According to research that was published in JAMA, the study said that untreated gestational diabetes is associated mostly with maternal development of disordered glucose metabolism but not as a result of overweight or obesity outcomes in their children.
To understand more about gestational diabetes and how it is associated with utero exposure and a long-term risk for maternal glucose metabolism and the childhood adiposity, the researcher did a follow up on cohort of 4,697 mothers at their mean age of 41years and also this follow up was extended to 4,832 children at their mean age of 11years.
During the follow-up period, 10 to 14 years postpartum, 14.3% of mothers meet criteria of for gestational diabetes. In patients found with gestational diabetes, about half 50.2% were found to have developed the disorder of glucose metabolism compared with 20.1% who did not have gestational diabetes. In women with this gestational diabetes, about 10.7% had type 2 diabetes and 41.5% had prediabetes; comparatively, for participant with gestational diabetes 1,6% had type 2 diabetes and 18.4% had prediabetes.
And in the children whom mothers had gestational diabetes 39% of them were deemed overweight compared to 28% of children whose mothers did not have gestational diabetes. After some few adjustments of maternal variables, gestational diabetes was not found to be significantly associated with childhood overweight or obesity outcomes. It was also noted that childhood adiposity measures might be relevant for interpreting these finding.
During this research, researchers highlighted several limitations about the study including the percentage of individuals who met criteria for gestational diabetes and participated in the study was lower than in all eligible participants.
Despite this limitation, the researchers said that their study demonstrated that untreated gestational diabetes was associated with higher risk for a maternal disorder of glucose metabolism 10 to 14 years’ postpartum. The association of gestational diabetes with childhood overweight or obesity not statistically significant, this was according to Tyler Rice article.
This study review that although there is association between gestational diabetes mellitus and offspring adiposity is attenuated after adjustment for pregnancy obesity a positive association remains.