A new-study revealed that antibiotic therapy may be considered as an alternative to acute apendicitis over a surgery, the JAMA Network said in a report.
The five-year study concluded that within the first year, “70 patients who initially received antibiotics underwent appendectomy; an additional 30 antibiotic-treated patients underwent appendectomy within the 5-year timeframe of the study. Results showed that for those treated with antibiotics the cumulative incidence of appendicitis recurrence at 1, 2, 3, 4, and 5 years was 27.3 percent, 34 percent, 35.2 percent, 37.1 percent, and 39.1 percent, respectively,” a report said.
However, JAMA noted that while short-term antibiotics treatment is definitely an alternative for uncomplicated acute apendicitis, the long-term outcomes remain unknown.
There were 530 patients who joined the five-year study, JAMA said.
A ruptured appendix may possibly be a life-threatening condition. Medical experts said it usually happens in people between 10 and 30. In the United States, there are approximately 250,000 reported cases annually.
ScienceDirect said acute apendicitis is still the “most common abdominal emergencies requiring surgery.” However, its report added that “management with antibiotics is gaining more and more acceptance.”
“This clinical condition encompasses a wide spectrum of clinical presentations, from the uncomplicated form to the one with diffuse peritonitis. Treatment of uncomplicated acute appendicitis remains a matter of discussion,” said the report.
JAMA said in its report that “among patients who were initially treated with antibiotics for uncomplicated acute appendicitis, the likelihood of late recurrence within 5 years was 39.1 percent.”